| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_575bdaac3c2462e49d47caac9ecab376
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f4b0b97756edc3252a92525210dd08c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87ff027e8c2fa376a060ec342c92262a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e3881c87d96dcbbc47fea34bbc6ff648
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3904067554b72695a8a407cb1a5a4435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f5ef0e68a190669a8aea84eb19c83ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5dacc25871bb38c4e1efce37c8083e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0dedefe13092a03b917972fdcbb2b151 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-423
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-10 |
| filingDate |
2011-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa34c9c3435ba9cedf545cf6363dba6d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c3cb31746e619aa6775ebdf8cb572d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2049ee60be0ff3a9ae9f4b9be406ce7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eee12a9891ea8e169b39c484ca068ebb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eea8153e555857e7cc542f1c5512394
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3741e5805e59867e5dce2a245ff61d2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3d09b7e0e5289dd448280d8dcb1ec27 |
| publicationDate |
2012-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012059015-A1 |
| titleOfInvention |
Novel spiroheterocyclic compounds as mglu5 antagonists |
| abstract |
The invention is directed to methods of using antagonists selective for the metabotropic mGlu5 receptor to treat conditions of neuromuscular dysfunction of the lower urinary tract in a mammal. Provided are methods of treating a mammal suffering from a condition of neuromuscular dysfunction of the lower urinary tract by administering a selective mGlu5 antagonist. The selective mGlu5 antagonist may be administered alone or in combination with one or more additional therapeutic agents for treating such a condition. Also provided are methods of identifying selective mGlu5 antagonists that are useful for treating neuromuscular dysfunction of the lower urinary tract in a mammal. Methods for treating migraine and gastroesophageal reflux disease (GERD) using selective mGlu5 antagonists are also disclosed. |
| priorityDate |
2010-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |