| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e522ef22f01c13cd40d52aaee98332c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4df528a427f4bc7e35e5ccd29156f460
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f52ad634ae464ce526234658faee49f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5053f82a7cd17c60822674b657cfb89e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-147
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-50 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-78 |
| filingDate |
2010-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b3badddbce553a1ebf78a6745dea347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae32cba899aca078a1b4a340e87b65ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_676a982291abc11f04458244a4034d43 |
| publicationDate |
2012-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012053362-A1 |
| titleOfInvention |
Process for the Preparation of Cinacalcet and Salts Thereof, and Intermediates for Use in the Process |
| abstract |
There is provided a process for preparing a salt of the (R)- or (S)-isomer of 1-naphthylethylamine with mandelic acid or a derivative thereof, the process comprising reacting racemic 1-naphthylethylamine with mandelic acid or a derivative thereof to obtain the (R)- or (S)-isomer of 1-naphthylethylamine salt (III) with the acid. The salts also form an aspect of the present invention. There is also provided a salt of the (R)- or (S)-isomer of 1-naphthylethylamine with mandelic acid or a derivative thereof. There is also provided a process for preparing cinacalcet (I) or a salt thereof, the process comprising reacting an ester (II) with (R)-1-naphthylethylamine or a salt of (R)-1-naphthylethylamine and mandelic acid or a derivative thereof, to obtain cinacalcet, and optionally converting the cincalcet to a salt thereof. |
| priorityDate |
2009-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |