Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3648c613ffe4e8064ea76a8c4661e0bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63f5a7104807f2fbcfcfb190c127ff89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca32fd2a44fd326ffd027a75a57bd13f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac9aa0b4be87d486d63d7873b6a83f0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f1b18d24d045ac209aa861521211c18 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06 |
filingDate |
2009-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7182e9c16a652e7dbf30bc0ead271ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74f7ca25ca88e8ed1ba6f8b25d28ca81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85d3d700ddddec64a64d05850a2e7786 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9d24c54617c1395fb5bac7f72e1236c |
publicationDate |
2012-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012040848-A2 |
titleOfInvention |
Molecular signature of liver tumor grade and use to evaluate prognosis and therapeutic regimen |
abstract |
The present invention concerns a method to determine the gene expression profile on a sample previously obtained from a patient diagnosed for a liver tumor, comprising assaying the expression of a set of genes in this sample and determining the gene expression profile (signature). In a particular embodiment, said method enables to determine the grade of liver tumor, such as hepatoblastoma (HB) or a hepatocellular carcinoma (HCC). The invention is also directed to kits comprising a plurality of pairs of primers or a plurality of probes specific for a set of genes, as well as to solid support or composition comprising a set of probes specific for a set of genes. These methods are useful to determine the grade of a liver tumor in sample obtained from a patient, to determine the risk of developing metastasis and/or to define the therapeutic regimen to apply to a patient. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8628920-B2 |
priorityDate |
2008-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |