Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ff53c1528b8950d34c1bfe9bb827c64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc5ff184d22d1806bc58d388c1548365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e62898e7789eacc784f239af0e1ccea |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 |
filingDate |
2010-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d33622039d68bddb15ea06b6dbd141a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf0d94ebd2e6a8acebe5a7b7ff1c8e5e |
publicationDate |
2012-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012040451-A1 |
titleOfInvention |
Molecules able to modulate the expression of at least a gene involved in degradative pathways and uses thereof |
abstract |
A molecule being able to modulate the expression of at least a gene involved in degradative pathways so to enhance the cellular degradative pathways and prevent or antagonize the accumulation of toxic compounds in a cell and acting on a CLEAR element. Preferred molecules are: the TFEB protein, synthetic or biotechnological functional derivative thereof; chimeric molecule comprising the TFEB protein, synthetic or biotechnological functional derivative thereof; modulator of the TFEB protein activity and/or expression level. The molecule may be used in the treatment of neurodegenerative and/or lysosomal storage disorders. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4028025-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020210921-A1 |
priorityDate |
2009-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |