abstract |
This invention is directed to spiroheterocyclic compounds of formula (I): n n n n n n n n n n wherein n n n n n n n n n n k, j, p, Q, R 1 , R 3a , R 3b , R 3e , and R 3d are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, that are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of using the compounds are also disclosed. |