| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04d2e4811dc630e16db64e5f3af9b4bf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4718 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2011-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_412fbe4415e9f2514842da0a986c9bac |
| publicationDate |
2012-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012034627-A1 |
| titleOfInvention |
Diagnosis of benign and cancerous growths by measuring circulation tumor stem cells and serum annexina2 |
| abstract |
Provided herein is a method for diagnosing/prognosing a metastatic cancer in a subject by measuring and detecting one or more of CS-ANXA2, DCAMKL, Lgr5 or CS-ANAX2 and DCAMKL or CS-ANXA2 and Lgr5 positive circulating tumor stem cells in the subject's blood or plasma. Also provided is a method for distinguishing the presence of early stage primary cancer from advanced stage metastatic cancer in the subject by measuring and detecting AnnexinA2, CS-ANXA2 and DCAMKL−1 or Lgr5 in the blood or plasma. In addition, there is provided a method for distinguishing the presence of benign, pre-cancerous tumorous growths or cancerous tumors in the subject by measuring and detecting AnnexinA2 and circulating tumor stem cells positive for CS-ANXA2 and DCAMKL or CS-ANXA2 and Lgr5 in the blood or plasma. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10669473-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010291193-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016119013-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8945544-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10232345-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011085986-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017161100-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10067134-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015233932-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10335470-B2 |
| priorityDate |
2010-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |