Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_087bed7abab91ae0f927879f9fe8b273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2cb5dc851be945e580b59c81a765625 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84b9be27c339e9c8800ad4a39591f873 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b34bd7d032960db4cd78d752fb180f7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1780a8cc4234257e9915e6ae008681e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3d8200c34738d3f5f2a41b4fd8a6f6a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d0b761c90aa011ba2158cec8d371432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b4ef1740fd2dd198950e06fecce1452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48c4118d3961253c9cda738b699cfc9f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0036 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-16 |
filingDate |
2011-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9889b5db6554760a1328415fb41df7f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b5701c42e295dc962eb48deaf0ef9d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e5cd7666f3094e44bb7a6a47cea95ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6b9b25b94a8c7dbc193e45322f07b79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16bcf1d6382155db0328b615da64e17c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ebf6edce2df68a761922868b28fcd1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d4ca1820fdade46d796f5984fbb867a |
publicationDate |
2012-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012028324-A1 |
titleOfInvention |
Engineered microorganisms capable of producing target compounds under anaerobic conditions |
abstract |
The present invention is generlly provides recombinant microorganisms comprising engineered metabolic pathways capable of producing C3-C5 alcohols under aerobic and anaerobic conditions. The invention further provides ketol-acid reductoisomerase enzymes which have been mutated or modified to increase their NADH-dependent activity or to switch the cofactor preference from NADPH to NADH and are expressed in the modified microorganisms. In addition, the invention provides isobutyraldehyde dehydrogenase enzymes expressed in modified microorganisms. Also provided are methods of producing beneficial metabolites under aerobic and anaerobic conditions by contacting a suitable substrate with the modified microorganisms of the present invention. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180535-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015035244-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010143997-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188722-B2 |
priorityDate |
2008-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |