Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca110d2cc472ec59024b80637c97aadc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b3203bae97c3b0a6baaa786fd4de95e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e41651508566f0385833e1ba14a21ffd |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-26003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-04 |
filingDate |
2011-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b088e9b741f9080665336a768ba9d2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18a3a7965ae9d8461cb85fa3553f34e4 |
publicationDate |
2012-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012028312-A1 |
titleOfInvention |
Methods and compositions relating to polypeptides with rnase iii domains that mediate rna interference |
abstract |
The present invention concerns methods and compositions involving RNase III and polypeptides containing RNase III domains to generate RNA capable of triggering RNA-mediated interference (RNAi) in a cell. In some embodiments, the RNase III is from a prokaryote. RNase III activity will cleave a double-stranded RNA molecule into short RNA molecules that may trigger or mediate RNAi (siRNA). Compositions of the invention include kits that include an RNase III domain-containing polypeptide. The present invention further concerns methods using polypeptides with RNase III activity for generating RNA molecules that effect RNAi, including the generation of a number of RNA molecules to the same target. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8524680-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010298408-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9777275-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9796978-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10036025-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10196640-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9592250-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010221789-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010184039-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10626398-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106793-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8815821-B2 |
priorityDate |
2002-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |