Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d35eaa5bf82df2dace857e3fb337cc0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ddccd218a9c414d68cea22d2f31127b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33bff12ce630adebaa508e17351a9986 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8b40eece1efabffa392cd1ac53dbfa5 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D455-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-06 |
filingDate |
2011-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d1235169e748d4e2ed9f20011a7599c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a9a970d57522ec52ef498b82f1ea5a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83788afc6acebf64fc92d06490d2d71a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7f5279d9206f044aba51820c86a219d |
publicationDate |
2012-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012022260-A1 |
titleOfInvention |
PROCESS FOR THE PREPARATION OF PYRIDO [2,1-a] ISOQUINOLINE DERIVATIVES COMPRISING OPTICAL RESOLUTION OF AN ENAMINE |
abstract |
This invention relates to a process for the preparation of pyrido[2,1-a] isoquinoline derivatives of the formula n n n n n n n n n n wherein R 1 , R 2 , R 3 and R 4 are defined in the specification, comprising the optical resolution of an enamine of the formula n n n n n n n n n n n n wherein R 1 is lower alkyl, in the presence of an optical active resolving agent to form an (S)-enamine salt of the formula n n n n n n n n n n n n wherein RCO 2 − is the conjugate base of the resolving agent. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014152768-A1 |
priorityDate |
2006-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |