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filingDate 2010-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59b97b9c04f6734af356be921bb5d5cf
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publicationDate 2012-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2012015364-A1
titleOfInvention Method for the selection of endothelial cells death inducers via netrin-1 and its applications
abstract The present invention relates to an in vitro method for selecting a compound capable to induce the death of endothelial cells, preferably endothelial cells from vessels or neovessels. The invention further comprises the use of netrin-1 function inhibitors as compounds capable to induce the death of endothelial cells, preferably endothelial cells from vessels or neovessels of tumor expressing netrin-1. Finally, the invention relates to a kit for the selection of a compound capable to induce the death of endothelial cells.
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