Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41b3fb150c337d092eb3a3af6d8fefdb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8fe512dcfa7132c5840eded49a36033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16bbdf8d6d0741262911d51e5c9fee7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40da09681f3bd00bc88a58d1dfd51897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3db7923b8399b8e052eecd89c2dd551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb7ce8745175865c6357f7d5fe7fccf5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_885cfdb9f042241b5f731e23f41b7f3f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 |
filingDate |
2011-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d9295642b5c16b8d46da9b51be00def http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0a4e22c2ed705a6e5a683f80857a384 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e54b45021a6dcf647ce082994d5f3d4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56a68cc05d614b4abd240dc822831795 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a632134e41ad8aef2904b2c0c8063e1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af9159653d31d05593b70ca0d70a6429 |
publicationDate |
2012-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012010240-A1 |
titleOfInvention |
CUT-POINT IN PTEN PROTEIN EXPRESSION THAT ACCURATELY IDENTIFIES TUMORS AND IS PREDICTIVE OF DRUG RESPONSE TO A PAN-ErbB INHIBITOR |
abstract |
A cut-point in the quantitative measurement of PTEN protein expression that accurately identifies tumors with two inactivated alleles of the PTEN gene. Patients with a normalized PTEN score of PTEN null will be treated with a pan-ErbB tyrosine kinase inhibitor. A normalized PTEN protein expression score is obtained by comparing the tumor PTEN OD expression value with the non-malignant PTEN OD expression value. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019018553-A1 |
priorityDate |
2010-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |