http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012004457-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93f59d2608b87b788ca8ce527a19f27e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61e2384a6ccd9c5761e5fe33edcceb54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b672ae82d4d6ed03794b61c28dbb3885 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C321-04 |
| filingDate | 2009-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_295ca3304a44585334675580c7ddd305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ceca9c5f44d606aabcb3ada50e2a3a2 |
| publicationDate | 2012-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2012004457-A1 |
| titleOfInvention | Method for producing peptide |
| abstract | An object of the present invention is to provide a novel method for producing a peptide utilizing a ligation reaction in which ligation efficiency is excellent and side reactions to other functional groups in the peptide are hard to occur, in comparison with the conventional native chemical ligation methods utilizing the thiol auxiliary group. The present invention provides a method for producing a peptide which comprises a step of causing a first peptide and a second peptide to react in the presence of a reducing agent to obtain a ligated product of the first peptide and the second peptide, wherein the first peptide contains, at the C-terminal end, an amino acid derivative having a thioester group, and the second peptide contains, at the N-terminal end, a serine or threonine derivative having a thiol auxiliary group. |
| priorityDate | 2008-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 212.