http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012003274-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b326e3e71a13419865d3508a5278e6c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30e228bbe5892cc822253a7e148c1550 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57f927d7c7cdf95c780fe0f292378e35 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D327-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D327-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 |
| filingDate | 2010-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3efad2631a5051e37944e04474e3728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7728177f8b6ff07a391668ad153dc6c6 |
| publicationDate | 2012-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2012003274-A1 |
| titleOfInvention | Oral sustained release antidepressant formulation |
| abstract | Pharmaceutical presentations or phenoxathiin-based MAO-A inhibitors are disclosed whereby the MAO receptors are capable of sustained release in the digestive tract. Particular phenoxathiin-based MAO-A inhibitors include those of the following formula: wherein n is 0, 1 or 2; R 1 is a branched or straight chain C1-5 alkyl or C3-6 cycloalkyl optionally substituted with hydroxyl, or one or more halogens; and X 1 , X 2 , X 3 , X 4 , and X 5 are either all hydrogens or one or two of X 1 , X 2 , X 3 , X 4 , and X 5 are halogen and the remainder are hydrogens, with the proviso that when n is 0 or 1 and each X is hydrogen, R 1 is not methyl. A wide variety or sustained release mechanisms can be utilized so as to provide gradual release of the active ingredient after ingestion as a pharmaceutical presentation, such as a tablet or capsule. Presentations include sustained release tablets, sustained release capsules, capsules containing sustained release beads. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9634260-B2 |
| priorityDate | 2009-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 201.