| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b537903e07982da81c8ea081da33597f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4419151f58c7ae749f88e2065fdd6058 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-49 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-05 |
| filingDate |
2011-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f580c90678f74f18aebbb002b00ea6d |
| publicationDate |
2011-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011312902-A1 |
| titleOfInvention |
Cytoprotective thereapeutic agents for the prevention of reperfusion injury following ischemic stroke |
| abstract |
The present invention relates generally to the use of γ-glutamyl antioxidants, particularly γ-glutamyl-cysteine, as cytoprotective agents to prevent reperfusion injury (i.e., hemorrhagic transformation) of the blood-brain barrier during reperfusion following an ischemic stroke. The γ-glutamyl antioxidants can be used alone or used in combination with an agent which inhibits the reverse movement of Na/Ca exchange in the blood-brain barrier such as 2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea methanesulphonate (KB-R7943). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10953006-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10406156-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10028951-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10603316-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10201539-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3035931-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10016416-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11559524-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105592849-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015026339-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11160802-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10531655-B2 |
| priorityDate |
2005-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |