Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e83eda056d0c6646c5fa300cf3bd5c49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d55444126b55e1edeb40523a4818da76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0abc72f9bb3a5c71671a75af596a97 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-001 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2011-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_262e4f188d6c4c460e89a706560948c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97a936c84e38e63d8cf61e8f0376a22f |
publicationDate |
2011-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011311972-A1 |
titleOfInvention |
Dpyd gene variants and use thereof |
abstract |
Variants in DPYD gene are disclosed which can result in abnormal synthesis of DPD proteins and alteration of DPD activities. The invention provides methods for detecting the newly discovered genetic variants. The DPD genetic variants of the invention can be used as biomarkers in predicting toxicity to 5-FU and other drugs metabolized by the DPD enzyme. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2701375-C1 |
priorityDate |
2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |