| abstract |
This invention relates to novel saponin compounds of formula II wherein MBz denotes p-methoxybenzoyl, and R is selected from the group comprising C 6-10 aryl, C 6-10 aryl-C 1-4 alkyl-, C 1-18 alkanoyl, C 3-18 alkenyl, C 6-10 aryl-C(O)—, C 6-10 aryl-C 1-4 alkyl-C(O)—, wherein each of the groups can optionally be substituted. These compounds possess a selective cytostatic activity, useful, e.g., in the treatment of proliferative diseases. The invention further relates to methods of preparation of the novel compounds and to a pharmaceutical composition containing these compounds. |