| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_385b586b26e431be0c66d80c1fa0084f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c88562b491924083cd8fff6a62404b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ebe6af5f762122ebb7c476849ddfc3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53205f5563c6ff1c02a736a840ab4d3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd2422be502bae353d1c9fc99670f752
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8023a169f596c68ff7485b07e0d1a385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_896f3088fe3d13776df6c7aa943f486f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d761f829a76528be769e9128f051eaf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce847ec6f3c526d6644de6548083b140 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y113-12007 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate |
2011-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4962cab1479c65a15b3bb74a43a4def3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7e9eca665089816e27f2b7bbed3f2f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c1355375235fb91d7b8a6de17582919
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efa7c5ac1dbd8958cb32b971bba4bece
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29b65007317caae05944990ec8f72da3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8278cb281f0331edf4a46ec903cf2ad5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6dadf402a9ad06195fa11ae47b7183f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d486ee239b18852cc907a628d144c57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdf15e699186ec6c55f2141f17c42f8e |
| publicationDate |
2011-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011283373-A1 |
| titleOfInvention |
Mutant protease biosensors with enhanced detection characteristics |
| abstract |
A polynucleotide encoding a biosensor polypeptide comprising a modified circularly-permuted thermostable luciferase and a linker linking the C-terminal portion of the thermostable luciferase to the N-terminal portion of the thermostable luciferase. The modified circularly-permuted thermostable luciferase is modified relative to a parental circularly-permuted thermostable luciferase. The linker contains a sensor region capable of interacting with a target molecule in a cell. The modified circularly-permuted thermostable luciferase has an enhanced response after interaction of the biosensor with the target molecule relative to the parental circularly-permuted thermostable luciferase in the presence of the target molecule. Alternatively, the modified circularly-permuted thermostable luciferase has an enhanced response after interaction of the biosensor with the target molecule relative to the modified circularly-permuted thermostable luciferase in the absence of the target molecule. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9938564-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9023610-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015154006-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8669103-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005153310-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9290794-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8673558-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8183036-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9927430-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9359635-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11661623-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8809529-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10774364-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9790537-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11767517-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9045730-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9139836-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9840730-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9487520-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009305280-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011039257-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8574865-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010311096-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9951373-B2 |
| priorityDate |
2010-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |