Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90566c42a11706cca0151d76095a5187 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84f229ef53e30ada3dec9645e308c0a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c666474ffc0184da7e8aafe5f0b324d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-18 |
filingDate |
2009-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f85d9a69b5267f5057e0f95c9533f8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3ed140cae6b1d5f5850a198e91fcc03 |
publicationDate |
2011-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011282028-A1 |
titleOfInvention |
Method for identifying inhibitors of lipoteichoic acid synthase |
abstract |
The invention provides a method of identifying an inhibitor of LtaS comprising:n (a) providing bacteria which comprise a mutation in the mbl gene or homologue thereof; (b) culturing the bacteria of (a) in the presence of a test substance under conditions of low magnesium; (c) monitoring the growth of the bacteria;n nwherein growth or more rapid growth of the bacteria compared to growth in the absence of the test substance is indicative that the test substance is an inhibitor of LtaS. |
priorityDate |
2008-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |