http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011275068-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b0c198757da18cf77dfbdcef00abb70 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2010-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64718ceb67b136dc1b76c8791b108de0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3521b68cae59cdcac3e1d0ef181d83fe |
| publicationDate | 2011-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2011275068-A1 |
| titleOfInvention | Method |
| abstract | The present invention relates to a combination method for A) measuring the copy number frequency of one or more nucleic acid sequences in a sample; and B) analysing the sequence of at least part of the nucleic acid sequence(s), wherein method A) comprises the steps of:n (i) providing one or more (e.g. a plurality of) aliquot(s) of the sample, wherein each aliquot comprises nucleic acid in an amount that is less than one genome per aliquot; (ii) amplifying one or more nucleic acid sequences in each of the aliquot(s) in a first amplification reaction; (iii) amplifying in a second amplification reaction one or more nucleic acid sequences in each of the aliquot(s) obtained or obtainable from step (ii), wherein at least one of the nucleic acid sequences is a test marker; and (iv) calculating the copy number of the test marker by comparing the number of amplified products for the test marker with a reference marker and wherein method B) comprises the step of analysing at least part of the sequence of an amplification product from the first and/or second amplification reaction. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015331867-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10025831-B2 |
| priorityDate | 2010-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.