| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59c6a921f33fe0adc58c2b6177184515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a92445b03d3abcd046386534d7f3b88f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_471357c16fd4ce68bc752c8a4eb208cd |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| filingDate |
2011-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_332cae8cbbc0e91e24955451783fed0c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5330dacdadf59c6a888ea6e735cde197
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a35ccea698b1ebc90bc9079ef867808 |
| publicationDate |
2011-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011268710-A1 |
| titleOfInvention |
Methods of treating stroke using stem cell-like menstrual blood cells |
| abstract |
A cell type that is a complete match of the transplant recipient appears as an optimal scenario to open treatment options to a large patient population with minimal complications. The use of autologous bone marrow or umbilical cord blood has been proposed as a good source of stem cells for cell therapy. Menstrual blood is found to be another important source of stem cells. Assays of cultured menstrual blood reveal that they express embryonic like-stem cell phenotypic markers and neuronal phenotypic markers under appropriate conditioned media. Oxygen glucose deprivation stroke models show that OGD-exposed primary rat neurons, co-cultured with menstrual blood-derived stem cells or exposed to the media from cultured menstrual blood, exhibited significantly reduced cell death. Transplantation of menstrual blood-derived stem cells, either intracerebrally or intravenously, after experimentally induced ischemic stroke in adult rats also significantly reduced behavioral and histological impairments compared to vehicle-infused rats. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014123516-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10149894-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10071144-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022387506-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105072914-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017064670-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10874723-B2 |
| priorityDate |
2008-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |