Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba02f01e4ca8c0846c4c3942fbfd83b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7403e984d2804d1ec664e0cc31922b7 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-54 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C47-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-04 |
filingDate |
2008-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd5863b5e7c27c2b7cad8791b0b7eef0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_185fa3a0e4543adb18cb91944176e1a7 |
publicationDate |
2011-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011263696-A1 |
titleOfInvention |
Proanthocyanidins from cinnamon and its water soluble extract inhibit tau aggregation |
abstract |
Compositions comprising proanthocyanidin compositions (e.g. those extracted from cinnamomum species) that are observed to bind tau and inhibit its aggregation as well as methods for making and using such compositions are disclosed. In certain embodiments of the invention, the proanthocyanidins can be used as a probe to identify and/or characterize tau isoforms in a variety of contexts. In other embodiments of the invention, these compositions are used in methods designed to treat neurological disorders associated with tau aggregation (e.g. Alzheimer's disease). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8568805-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009182037-A1 |
priorityDate |
2007-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |