| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c7b21ab23ac7073b54fdd2552e4d191
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81390d80019c0e8db1f21030ed91bd68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c10c4187c948207e7bf7d8eb242e2e36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08805c563877d2ec6e01bc3872dd8e89 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D273-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D273-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 |
| filingDate |
2011-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13e37a7679b44ef10d3f270443c35973
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2023f28a495b888303096e3f476059ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcfa72f02917781d1c3e85f70b30f99f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_075d4ca7936ef98993576a13cde9aaa1 |
| publicationDate |
2011-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011257254-A1 |
| titleOfInvention |
Adamantane Derivatives Of Aza-Crown Ethers And Their Use In Treatment Of Tumor |
| abstract |
The invention relates to adamantane diaza-crown ether derivatives and the use of mono and diaza-crown ether adamantine derivatives in treatment, especially in tumor treatment. Adamantane aza-crown ethers were obtained by reaction of the corresponding adamantane derived tosylates or adamantane acid chlorides with mono- and diaza-18-crown-6. The prepared compounds showed moderate (monoaza-18-crown-6) to strong (diaza-18-crown-6) antiproliferative and cytotoxic activity on several tumor cell lines, revealing their potential for inhibiting the growth of other tumor cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015188140-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11213512-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10463044-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014024168-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10791740-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2994433-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9707254-B1 |
| priorityDate |
2009-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |