http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011256579-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fab5a78161702097f97524ce6e5cdcd7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 |
| filingDate | 2009-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bc078c865b0a9f31a8cd8298f2fdf99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_504a8125e252342ac39548a80228ec2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c96f2598d24df4299a924acb52db5de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b51f30fde1699718b1bba7d670e38050 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13f51f60218cca9397fd05c64744b164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac9b8b899a3beafe7fb5415f88a9fad5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eccbd4135759ec355f1249f5766ece03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0c8805f9fc80d3e598b7bf06673748a |
| publicationDate | 2011-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2011256579-A1 |
| titleOfInvention | Method for Verifying and/or Identifying Hormonally Effective Substances |
| abstract | The invention relates to a method for verifying and/or identifying hormonally effective substances using the pheromone system of yeast, to yeast cells for carrying out the method, and to the use thereof. The method according to the invention comprises the following steps: a) adding yeast culture medium or buffer to a sample which presumably contains a hormonally effective substance, b) thereafter contacting the sample with haploid yeast cells that possess features 1 through 3: 1. the DNA sequence coded for a heterologous hormone receptor is placed under the control of a constitutive promoter, 2. the DNA sequence coded for a yeast pheromone is placed under the control of a promoter that can be regulated by the hormone receptor, 3. a gene that is coded for a receptor for the yeast pheromone is constitutively expressed, wherein the activation of the hormone receptor by the hormonally effective substance leads to the expression and secretion of the yeast pheromone, and c) the physiological and/or morphological changes of haploid yeast cells are detected. |
| priorityDate | 2008-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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