| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c485e6b575b141a77347283d1e33a365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16858e8eb37c33227ecf675002c0f9cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1203c136551d1a7f32837f56ddab18b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f074abc704606659ee445f37c71c27aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d98e48489d25e726d432addf0f5f76b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_673d593b7606ece03af4f14c01dd0437 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24221 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-707
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
| filingDate |
2004-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f214206a40c14550aec5d7dede78cbb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f447990852d5f56837375fa3af8db1fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f3220de51404d6a5f5b2e121c4827a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07b106ae7163b867bd210bd823b08935
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a59f532ef5b4ae80a9f8ee70380f9d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb9818437664918144dd36254edcbede |
| publicationDate |
2011-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011250628-A1 |
| titleOfInvention |
Hcv replicons containing ns5b from genotype 2b |
| abstract |
The present invention features methods for enhancing the ability of a genotype 2b NS5B sequence to function in a replicon, for producing replicons containing a functional genotype 2b NS5B, and for using replicons to measure the ability of a compound to affect HCV replication that is sustained with the genotype 2b polymerase. Also featured is a genotype 1b NS4B adaptive mutation. The ability to produce replicons containing a functional genotype 2b NS5B is illustrated by the production of chimeric replicons based on HCV genotype 1b where substantially all the NS5B sequence is replaced with a genotype 2b NS5B. |
| priorityDate |
2003-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |