Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d5d546aa6cbfb52c137af7cafc36bf4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_673d2752f1805a76fcdb94b38f0518f8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-32 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 |
filingDate |
2009-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99a4a7e99378379e2c76cca35206c0d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b80cd17072e5ad6dd529e9bd8f5addac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b364d7f3df03cc692e6d0c414d709d31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65051785c039dcd184f09bf45748e0dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad85c567f7f026aab893e27de0c7b944 |
publicationDate |
2011-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011236900-A1 |
titleOfInvention |
Novel muts protein and method for determing mutation using the same |
abstract |
A method for determining the presence or absence of a mutation on the basis of the presence or absence of amplification with high reliability is provided. A target sequence including a target site contained in a sample nucleic acid is amplified using a primer that can hybridize to a region including the target site contained in the sample nucleic acid in the presence of a novel MutS having an amino acid sequence of SEQ ID NO: 2, and then the presence or absence of a mutation at the target site is determined on the basis of the presence or absence of amplification. The novel MutS binds more specifically to a mismatched base pair than to a fully-matched base pair, whereby an extension reaction caused by a mismatch-binding primer is suppressed. Thus, according to the present invention, the presence or absence of a mutation can be determined with high reliability. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021100941-A1 |
priorityDate |
2008-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |