http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011230427-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_081b337ae6ecbc10c82be1d4c82b6237 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d6a252056b0d8bd204f37277bd65e2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10b3723ed7561a87b3e24223be6dbc13 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-14 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate | 2011-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6a2aa01f441de1a9ef49adea1aaeaac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68e2b24cd785780a1d743253c8aca448 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70ed328f238b6dd6698e77cd2ac3b622 |
| publicationDate | 2011-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2011230427-A1 |
| titleOfInvention | Materials and methods for stabilizing nanoparticles in salt solutions |
| abstract | Sequence-specific polymers are proving to be a powerful approach to assembly and manipulation of matter on the nanometer scale. This has been most impressive in the case of DNA, and progress has been made toward templating inorganic nanoparticles using DNA nanostructures. One obstacle to this progress is that inorganic nanomaterials are often incompatible with DNA assembly conditions, which involve aqueous solutions high in either or both monovalent and divalent salt. Synthetic oligopeptide ligands have been shown by others to improve nanoparticle stability in high concentrations of monovalent salt. Ligands that are peptoids, or sequence-specific N-functional glycine oligomers, allow precise and flexible control over the arrangement of binding groups, steric spacers, charge, and other functionality. We have synthesized short peptoids that can prevent the aggregation of gold nanoparticles in high-salt environments including divalent salt, and allow co-adsorption of a single DNA molecule. This degree of precision and versatility is likely to prove essential in bottom-up assembly of nanostructures and in biomedical applications of nanomaterials. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113262719-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113275584-A |
| priorityDate | 2010-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 261.