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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20179aba9393ee12ef68440934bb5c29
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publicationDate 2011-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2011217707-A1
titleOfInvention Evaluation/screening method for diseases associated with d-amino acid utilizing da01-/-mouse
abstract Disclosed is an evaluation method which can rapidly discriminate a Dao −/− homozygote from a large number of animals produced in a mating experiment between a DAO enzyme deficient mouse and other disease model mice, to rapidly perform a quantitative measurement of the D-amino acids contained in a large number of samples. The invention provides a method for evaluating the effect of a test condition on a mouse tissue, or cultured tissue cells derived from the tissue. The method comprises the steps of: providing a Dao1 −/− mouse or the like; exposing the tissue from the Dao1 −/− mouse or the like, to the test condition; and analyzing the effect of exposing the tissue from the Dao1 −/− mouse or the like, to the test condition.
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priorityDate 2008-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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