| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8bc6d7e07cca0c16f01bcf4a891790c0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 |
| filingDate |
2009-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb60bc2af2baceec4f82b55488966484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d6afd17464a1c119879c1c50ed01d0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_452df1643796b67ecf269e9a40613c18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceda10b061f83b626b76cf10e319beba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_808415c4a64c1dc847aa0912dcd07406
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76ce67837d5c3ad48deadfd687588706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_815d1849152d05728de2ec260d4a4112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc5e7edcc86ffdaa401aaf996858941d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c545fec8fb20db39fef235ebc1172ff7 |
| publicationDate |
2011-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011207930-A1 |
| titleOfInvention |
Improved production method for adefovir dipivoxil |
| abstract |
The present invention relates to an improved method of preparing adefovir dipivoxil of Formula 1. The method of the present invention is characterized by using dimethylsulfoxide as a reaction solvent, and comprises a process of preparing adefovir dipivoxil of Formula 1 by allowing adefovir of Formula 2 to react with chloromethylpivalate at a reaction temperature of 30 to 50° C. under the presence of dimethylsulfoxide and triethylamine solvents. |
| priorityDate |
2008-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |