Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a9e9ce63eb0bbf3658453fb50a6d9b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
filingDate |
2008-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e233a2bacb3d4185612f86ffc2c9616e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8a3cc4af679995262839a602f379544 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d73a029308671f8b5203bfd667820df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb6be688e756564bc68486ce19fed313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7500c2358cfa5f5244ab1b5b1681d103 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab8eb27caad1cf5157b36ee33c39c438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea72debfc6bb7ea1bbc85a1130f6385e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b5c38b4313a65ed44c756928141aa84 |
publicationDate |
2011-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011201812-A1 |
titleOfInvention |
Process for the manufacture of an indolinone derivative |
abstract |
The present invention relates to a process for the manufacture of a specific indolinone derivative and a pharmaceutically acceptable salt thereof, namely 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone and its monoethanesulfonate, to new manufacturing steps and to new intermediates of this process. |
priorityDate |
2007-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |