http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011189754-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d97e62338300afc0c0bfa57b698799b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95a54570b422bd2ee17d950e07fd3911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5c3f7688db7a0079cc107634f3d99a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c682c345b77a187a991f3cef8673c5c4 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-35 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96 |
filingDate | 2011-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a1babd02842201052f77126527f46ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4573b4c33387a7055a057934d99bad6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3f20af7ca1f8467e78837350e7e085f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87522069bc87b2b2a54ee4a8ee94a8c1 |
publicationDate | 2011-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2011189754-A1 |
titleOfInvention | Fusion protein comprising an e. coli chaperone protein and a human chaperone protein |
abstract | The invention discloses the cloning, expression and uses of a chimeric fusion protein with superior chaperone and folding activities compared to the wild type chaperones. This invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule containing nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for an FK506 binding protein (FKBP) or an FK506-binding-protein-like domain (FKBP-like domain). In particular, this invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule containing nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for a human FKBP type peptidyl-prolyl-cis/trans isomerase (PPIase), methods of producing these chimeric fusion proteins and their uses as folding helpers in the production of other proteins and in the process of the production of vaccines or pharmaceuticals, and as folding helpers for performing immunoassays. |
priorityDate | 2006-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 757.