| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate |
2009-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65c76ee0d5865fe61c94b987fa6802bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58dd2ddc8698ea54c18c9907bb31fbac |
| publicationDate |
2011-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011182902-A1 |
| titleOfInvention |
Recombination Sequence (RS) Rearrangement Frequency as a Measure of Central B Cell Tolerance |
| abstract |
The invention relates to methods and materials for diagnosing an autoimmune disease such as SLE, Type 1 diabetes, and the like. More particularly, the invention relates to methods and materials for assessing the frequency of recombination sequence (RS) rearrangement as a novel marker for an autoimmune disease. Such an assay can allow clinicians to diagnose an autoimmune disease based on the RS rearrangement frequency in an autoimmune patient as compared to an otherwise healthy control. In addition, the method includes identifying individuals who are at increased risk of developing autoimmunity. The method may also be helpful in directing the type of therapy and monitoring the effects of therapy in patients with autoimmune or non-autoimmune conditions. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10590483-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11118176-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10119134-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10392614-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016017428-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10837060-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9816088-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10876107-B2 |
| priorityDate |
2008-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |