| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0f4f8190960626ec922a1f03bcd4aba |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C261-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D301-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-00 |
| filingDate |
2009-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9e95e42478b4c1a43ca3d8d86de1975
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f08cc1778fc64bfc688b3a59bbe3898
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc46da960370453bf9f78c2a24ee87ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_307942fb7d1ba3328b16a3cc9e78332b |
| publicationDate |
2011-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011178305-A1 |
| titleOfInvention |
Process for the preparation of 3,4-epoxy-2-amino-1-substituted butane derivatives and intermediate compounds thereof |
| abstract |
The present invention relates to a process for the preparation of threo-3,4-epoxy-2-amino-1-substituted butane derivatives represented by general Formula I which comprises reacting compound of Formula III or salt thereof with an active ester of acid of Formula IV and treating the product thereof with base. The carbon atom bonded to the radical R 3 in Formula I and IV is in the (R)-, (S)- or (R,S)-configuration. The compounds of Formula I and III, particularly in their (2S,3R) configuration are useful intermediates for the preparation of atazanavir bisulfate. |
| priorityDate |
2008-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |