| abstract |
The invention relates to a filter system for removing activated PMNs and mediators which are responsible for the activation thereof, and optionally mediators which are simultaneously, but independently of activated PMNs, responsible for a state of illness from body fluids, process for production thereof and use thereof. The inventive filter system for continuous removal of activated PMNs from blood consists of molecules which recognize and bind activated PMNs, molecules which recognize and bind PMN-activating mediators, molecules which recognize and bind C3a and/or C5a, biocompatible surfaces (carriers) on which the molecules a., b. and c. are bound covalently or adsorptively, a casing for accommodating the active carriers, valves and tubes. The field of use of the invention is medicine. |