http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011171642-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33e0cb77260827966a920f9232dfb4f9
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
filingDate 2009-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_475c6afdd30ce46e9a22854aa0d4b030
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f2c42022b430e55dcce64c4be368ad3
publicationDate 2011-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2011171642-A1
titleOfInvention Analysing Methylation Specific PCR by Amplicon Melting
abstract The present invention provides a method of evaluating DNA methylation in a sample. The method comprises (i) reacting the DNA with an agent that differentially modifies methylated cytosine and non-methylated cytosine to produce modified DNA, (ii) amplifying the modified DNA by methylation specific PCR to produce amplified DNA, and (iii) subjecting the amplified DNA to melting analysis. In the method the methylation specific primers are selected such that the sequence between the primers includes a region of known sequence variation and/or at least one cytosine nucleotide.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018165366-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109295178-A
priorityDate 2008-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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