| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ece82f7fd5baf11c67732d3e516b17fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c28f3e42d6af654145d5588488c538f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d7a0e6c751af220bb26f59e77cc62c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_622a82189ec792f11887f416bfa895aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4336e75383858f1d4bd31ab159b13050
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a75abdbf7187812e9ee9e16353907ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_becbf6ed1979523c4e7ca269ee652a78 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A90-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-40 |
| filingDate |
2009-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f28e2cc0d6764f93749655c38009f03a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_372c635ede578b434d4c6ed1d71ce4f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_836e3b650a3d9aa4426a2af7ffe481d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2229f48570731a860a0c44a1af08fb78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed57a75b6a6a8cf922e5fb9711aa6c2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e732cc494cbefc5af492650e5216db3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53b3f763cb54c07b73b30b6544bad763 |
| publicationDate |
2011-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011171200-A1 |
| titleOfInvention |
Protein c rs2069915 as a response predictor to survival and administration of activated protein c or protein c-like compound |
| abstract |
Provided herein are methods, oligonucleotides and peptide nucleic acids, compositions and kits for predicting a subject's response to treatment with activated protein C or protein C-like compound or susceptibility to major organ dysfunction or susceptibility to an inflammatory condition. The method generally comprises determining a genotype of said subject at one or more of polymorphic sites in the subject's protein C gene selected from one or more of the following: rs20069915 and one or more polymorphism sites in linkage disequilibrium thereto, selected from one or more of the following: rs2069910; rs2069916; rs2069924; rs2069931; rs1799808; rs2069920; and rs6714364 and may further involve comparing the determined genotype with known genotypes for the polymorphism that correspond with an improved response to treatment with activated protein C or protein C-like compound or correspond to susceptibility to major organ dysfunction or susceptibility to an inflammatory condition. Also provided are methods of treating subjects with an anti-inflammatory agent or anti-coagulant agent based on the subject's genotype. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110734970-A |
| priorityDate |
2008-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |