http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011166364-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_139aff3556869a0208383f5dac575e98 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 |
| filingDate | 2009-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef6917526cc336be209ff98f909772e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_122aa436fb98e1aa333c477b79f617f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7707d8e7c170157af86b45c63cc9e64e |
| publicationDate | 2011-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2011166364-A1 |
| titleOfInvention | Synthesis of 3--5-[2-(phenylsulfonyl)ethyl]-1h-indole |
| abstract | The present invention refers to the synthesis of 3-{[(2R)-1-methylpyrrolidin-2-yl]methyl}-5-[2-(phenylsulfonyl)ethyl]-1H-indole, a drug known by the name Eletriptan, or of its salts. In particular, the present invention regards a process for the synthesis of Eletriptan or of its salt, comprising the following steps: a) Salifying the intermediate of Formula (6), using a dicarboxylic acid to obtain a derived salt; b) Optionally, purifying said raw salt obtained according to step a) by solvent crystallization to obtain a purified salt of the intermediate of Formula (6); c) Converting said salt of the intermediate of formula (6) according to step a) or said purified salt according to step b) into an intermediate of formula (10); d) Converting the intermediate of Formula (10) into Eletriptan or its salt. |
| priorityDate | 2009-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.