Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce3570fbc10461e10753ee644f6b5eed http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f616f3c2ea3a517c5ceee05fda51efcd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aad0708c0a018382737a360d8ce81f4e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-40 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2009-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7a7fbd4a1e716f449d99959d0eaecdf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1907c2bce8cc32875c5556331039efe8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df791b530a244f2a1348e11a82623f16 |
publicationDate |
2011-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011165578-A1 |
titleOfInvention |
Methods for detecting and quantifying oversulfated glycosaminoglycans |
abstract |
The invention relates to novel methods for detecting and/or quantifying oversulfated or persulfated glycosaminoglycans based on inhibition of nucleic acid polymerases. The methods can be utilized to detect and quantify oversulfated or persulfated glycosaminoglycans in pharmaceutical preparations, such as heparin preparations or therapeutic medical devices. When used to detect or quantify oversulfated glycosaminoglycans in heparin containing solutions, the samples are prepared by treatment with heparinases to degrade the heparin. Titration of the inhibition of the activity of the polymerases allows quantitation of the oversulfated glycosaminoglycans in the sample. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10345259-B2 |
priorityDate |
2008-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |