Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_315ae544538aaeac6d1f4eed6754e4bb |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B02C17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 |
filingDate |
2010-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af4f235ad9ad9f6402ee0fc1819c88c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b67e68e2d2817937302b5be6a2750d0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_842c28303041b9983f1785b70d9845be |
publicationDate |
2011-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011151014-A1 |
titleOfInvention |
Microcrystalline cellulose and calcium carbonate compositions useful as recompactible pharmaceutical excipients |
abstract |
Coprocessed compositions containing microcrystalline cellulose and calcium carbonate, wherein the weight ratio of microcrystalline cellulose to calcium carbonate is relatively high, are useful as excipients in the preparation of solid dosage forms containing active pharmaceutical ingredients, particularly those prepared by processes involving multiple compaction steps. Such compositions may be obtained, for example, by preparing aqueous slurries or wet masses of microcrystalline cellulose and calcium carbonate and drying such slurries or wet masses to produce particulate products. The coprocessed products exhibit improved recompactibility, as compared to coprocessed products having lower microcrystalline cellulose:calcium carbonate weight ratios or as compared to physical dry blends of the two excipients. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018078506-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014165241-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10172944-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021219458-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109330985-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102614519-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10617648-B2 |
priorityDate |
2009-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |