http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011144327-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 |
filingDate | 2011-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be4a92bab913e8b38fa87509d9e333d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c779fc304d4f33ffc4bd087df7c2766 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c4e870f8d0aa1f05a645740ad5fe797 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_163e5881cf7d68a85d3de2f9d3028421 |
publicationDate | 2011-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2011144327-A1 |
titleOfInvention | Process for the synthesis of azetidinones |
abstract | A process is provided for preparing azetidinones useful as intermediates in the synthesis of penems and as hypocholesterolemic agents, comprising reacting a β-(substituted-amino)amide, a β-(substituted-amino)acid ester, or a β-(substituted-amino)thiolcarbonic acid ester with a silylating agent and a cyclizing agent selected from the group consisting of alkali metal carboxylates, quaternary ammonium carboxylates, quaternary ammonium hydroxides, quaternary ammonium alkoxides, quaternary ammonium aryloxides and hydrates thereof, or the reaction product of: (i) at least one quaternary ammonium halide and at least one alkali metal carboxylate; or (ii) at least one quaternary ammonium chloride, quaternary ammonium bromide, or quaternary ammonium iodide and at least one alkali metal fluoride, wherein a quaternary ammonium moiety of the cyclizing agent is unsubstituted or substituted by one to four groups independently selected from the group consisting of alkyl, arylalkyl and arylalkyl-alkyl. |
priorityDate | 2004-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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