http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011143455-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79ab4ada18f677c855a9ebb5a74f8188 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-961 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-962 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-973 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-971 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-819 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6887 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2011-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bd034ed79967d49fa39db8abe957f59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77a80d6916222ad14940d541c6f2396b |
publicationDate | 2011-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2011143455-A1 |
titleOfInvention | Novel methods for the assay of troponin i and t and complexes of troponin i and t and selection of antibodies for use in immunoassays |
abstract | Assay systems and specialized antibodies for the detection and quantitation of troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in various conformations in the blood, the ratios of the monomeric troponin I an T and the binary and ternary complexes, as well as which form of troponin present in the blood, may be related to the metabolic state of the heart. Disclosed is a system to determine the presence of a troponin form or a group of troponin forms in a sample of whole blood, serum or plasma. n Disclosed is a stabilized composition of troponin; the stabilized composition can comprise a stabilized composition of troponin I, wherein the troponin I is oxidized, the troponin I can be unbound or the troponin I can be in a complex. n Disclosed is a method for improving the recovery of troponin I or T from a surface used in immunoassays. n Also disclosed are antibodies which recognize, unbound troponin forms, the forms of troponin in binary complexes, the ternary complex of troponin I, T and C, and the conformations of troponin I having intramolecularly oxidized and reduced cysteines. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8969018-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011065210-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10634681-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009275512-A1 |
priorityDate | 1995-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 436.