http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011143384-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_74d3a9f0dff3d3664f8f84d5aba0da99 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-062 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 |
| filingDate | 2008-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e451741e4cdad99b81242f6a5020ee8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05cb627fdea5cdafb9b409bd6066108e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b47277e49e20cedb42e0c54c8baf4724 |
| publicationDate | 2011-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2011143384-A1 |
| titleOfInvention | Methods of peptide modification |
| abstract | The present invention relates to a method of improving the resistance of a peptide or peptidomimetic to degradation by trypsin which comprises incorporating into said peptide or peptidomimetic a C-terminal capping group of formula (I): X—Y—Z (I) wherein X is a N atom, which may be substituted by a branched or unbranched C 1 -C 10 alkyl or aryl group which group may incorporate up to 2 heteroatoms selected from N, O and S; Y represents a group selected from —R a —R b —, —R a —R b —R b ,- and —R b —R b —R a — wherein R a is C, O, S or N, and R b is C; each of R a and R b , may be substituted by C 1 -C 4 alkyl groups or unsubstituted; and Z is a group comprising 1 to 3 cyclic groups each of 5 or 6 non-hydrogen atoms, 2 or more of the cyclic groups may be fused and one or more of the cyclic groups may be substituted; the Z. moiety incorporates a maximum of 15 non-hydrogen atoms; and wherein the bond between Y and Z is a covalent bond between R a or R b of Y and a non-hydrogen atom of one of the cyclic groups of Z. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9556223-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11548912-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011301076-A1 |
| priorityDate | 2007-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 279.