http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011136136-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efd09c296645384c4e1c770411f7aa01 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-962 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25625 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-2525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-107497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-108331 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-9493 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2011-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09c12065e025fbfe41b0d2be0e91a900 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_587a8481f433bd8ad1c1a504a5f8b639 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9af7f4c8b57cc1d0ccd06256e2d956ab |
| publicationDate | 2011-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2011136136-A1 |
| titleOfInvention | Methods For Detection Of Hydrophobic Drugs |
| abstract | Methods and reagents are disclosed for pretreating a sample suspected of containing a hydrophobic drug for conducting an assay method for detecting the hydrophobic drug. A combination is provided in a medium. The combination comprises (i) the sample, (ii) a releasing agent for releasing the hydrophobic drug and the metabolites from endogenous binding moieties, and (iii) a selective solubility agent that provides for substantially equal solubility of the hydrophobic drug and the metabolites in the medium. The selective solubility agent comprises a water miscible, non-volatile organic solvent and is present in the medium in a concentration sufficient to provide for substantially equal solubility of the hydrophobic drug and the metabolites in the medium. The medium, which may further comprise a hemolytic agent, is incubated under conditions for releasing the hydrophobic drug and the metabolites from endogenous binding moieties. For conducting an assay for the hydrophobic drug, the above pretreatment is performed and to the medium is added reagents for determining the presence and/or amount of the hydrophobic drug in the sample wherein the reagents comprise at least one antibody for the hydrophobic drug. The medium is examined for the presence of a complex comprising the hydrophobic drug and the antibody for the hydrophobic drug, the presence and/or amount of the complex indicating the presence and/or amount of the hydrophobic drug in the sample. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11573223-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10383860-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013169689-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9658218-B2 |
| priorityDate | 2007-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 194.