http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011130587-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a36c66685971b78daf233b5999ead4c2 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-32 |
filingDate | 2009-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e6b1b9a5198b58c6648c87a5a1d86d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff13a2b0ec5ebdcbfdff6d121b90a650 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18e1ea5bfd859085851643632db486e2 |
publicationDate | 2011-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2011130587-A1 |
titleOfInvention | Process for preparing r-beta-amino phenylbutyric acid derivatives |
abstract | Disclosed is a process for preparing single enantiomers of beta-amino phenylbutyric acid derivatives and pharmaceutically acceptable salts thereof, which affords the desired compounds having special optical configuration. The process comprises a step of chemical synthesis and a step of resolving the optical isomers of beta-amino phenylbutyric acid derivatives with a resolving agent. The resolving step comprises reacting the optical isomers with resolving agents, such as di-para-toluoyl-L-tartaric acid and di-para-toluoyl-D-tartaric acid. The obtained R-beta-amino phenylbutyric acid derivatives (I) have high optical purity, and the total yield of the accumulative resolution of the laevo and the dextro isomer is up to above 70%. |
priorityDate | 2008-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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