| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a36c20329430ad62d297a93a6a8aefa4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-204998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-497
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0455
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00 |
| filingDate |
2010-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_513d63267e8a6acbc216a525d6a888d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b293e454e20ed691908fe5a36d247ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f04fd39913118a769a98e5c7d86fadf9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb48bd939028a33564a7d383e21821b6 |
| publicationDate |
2011-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011111510-A1 |
| titleOfInvention |
Methods to evaluate cytochrome p450 2c19 isoenzyme activity using a breath test |
| abstract |
The present invention relates, generally to a method of determining and assessing cytochrome P450 2C19-related (CYP2C19) metabolic capacity in an individual mammalian subject via a breath assay, by determining the relative amount of 13 CO 2 exhaled by the subject upon intravenous or oral administration of a 13 C-labeled CYP2C19 substrate compound. The present invention is useful as anon-invasive, in vivo assay for evaluating CYP2C19 enzyme activity in a subject using the metabolite 13 CO 2 in expired breath, to phenotype individual subjects and to determine the selection, optimal dosage and timing of drug administration. |
| priorityDate |
2006-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |