Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f2ad6b4d4081ba2d8724466631ab640 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
filingDate |
2010-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20bd9a3203337bd319d25d09426250e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_229a33101465a59b79f9dab5f8a0a9a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4deb5ec4649def2328973e900688927d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_486ced32692285a5f78a88f4fed6dc62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d07e0fcb5ab1b1d2dafccc30490225f |
publicationDate |
2011-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011086423-A1 |
titleOfInvention |
Cellular Targets for Treatment of Retroviral Infection |
abstract |
Cellular targets for anti-retroviral drug development are disclosed. The cellular targets comprise ATR kinase and its relevant substrates, based on the identification of the ATR kinase as required for the final step of retroviral DNA integration. Assays for identifying modulators of retroviral integration via the ATR kinase pathway are disclosed, as well as modulators identified by such assays. Pharmaceutical preparations and methods of their use in treating retroviral infection are also disclosed. |
priorityDate |
2002-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |