| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc06cad2b58bbfcc30e3c96a6eb6c926 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1854
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-186
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1833
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0009
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6923
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-551 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2010-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9e1c9ed1a6a9d42f6aa2d5ca54669ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcfe5ebfde1975f0a26ce432b626ff45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f7717f9e901e7956a8373b4e59e36a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78c2e1e8feaf64ee7090d7178ca6b3d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa460eeb3744e5ac53b88b98c3f76b2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e81db8446b13cd9f11ffacc5a78cdb92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_947800a990dbc002f9f9ff9999032a4c |
| publicationDate |
2011-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011085987-A1 |
| titleOfInvention |
Folic acid-mediated magnetic nanoparticle clusters for combined targeting, diagnosis, and therapy applications |
| abstract |
The preparation method of the magnetic nanoparticle (MNP) includes steps of: (a) reacting folic acid (FA) with Pluronic F127 (PF127) to form FA-PF127; (b) reacting poly(acrylic acid) (PAA) with FeCl3 to form PAA-bound iron oxide (PAAIO); and (c) reacting FA-PF127 with PAAIO via N-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDAC) mediation to form FA-PF127-PAAIO. FA-PF127-PAAIO is nontoxic and shows the superparamagnetic property at room temperature. The Nile red-loaded FA-PF127-PAAIO can be performed as the chemotherapy agent and the contrast agent on magnetic resonance (MR) imaging. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113144206-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11458136-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103773373-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108096589-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016117769-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11311545-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016044716-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10500164-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115227820-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102276813-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112641958-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110501208-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015034381-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10359678-B2 |
| priorityDate |
2009-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |