http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011082306-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c592009b8c77c96c2b19b855287b374 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0fdf7e8538a3e5866347798c658cb04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_659126995f1293c310553b159743bb0c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 |
| filingDate | 2009-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a691c048a008dbb929c25255ae8940f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2996cc20529f4b8f22b22831d3772ea7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b77e378464162fbcc3652d2617a2467 |
| publicationDate | 2011-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2011082306-A1 |
| titleOfInvention | Birch reduction of steroid substrates via alkali metal - silica gel materials |
| abstract | Steroids are well known, medicinal relevant, chemical entities. There are numerous steroids which have fully or partially reduced ‘A’ rings. These fully or partially reduced ‘A’ rings have been reduced in the past through Birch and other dissolving metal reductions. Novel reducing conditions for steroid substrates are described which utilizes stabilized alkali metal-silica gel materials. The invention relates to a method for reducing a double bond within a steroid by contacting an unsaturated steroid having a phenyl ring with a Stage 0 or Stage I alkali metal-silica gel material in the presence of a proton source under reaction conditions sufficient to form a reduced steroid having a diene structure. |
| priorityDate | 2008-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.