http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011076718-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate | 2009-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2eac35445ea1d3c8ad08781514d6aa50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_933d6e43f92315ddeed0b05a5478cd19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c627a9a44ba429cfa111bd409444eaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fa7fa937aa490140eeeabc5f11363e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd7abe90e3034c090c218bf2c5d6dade |
| publicationDate | 2011-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2011076718-A1 |
| titleOfInvention | In vivo incorporation of an unnatural amino acid comprising a 1,2-aminothiol group |
| abstract | The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate unnatural amino acids that comprise a 1,2 aminothiol group into polypeptides. The invention provides translation systems in which polypeptides comprising unnatural amino acids that comprise a 1,2 aminothiol group can be produced. The invention also provides methods for producing polypeptides containing unnatural amino acids that comprise a 1,2 aminothiol group. Also provided by the invention are compositions comprising orthogonal aminoacyl-tRNA synthetases that preferentially aminoacylate a cognate orthogonal tRNA with unnatural amino acids that comprise a 1,2 aminothiol group. The invention provides methods for the synthesis of the unnatural amino acid 2-amino-3-(4-(2-amino-3-mercaptopropan-amido)phenyl)-propanoic acid. |
| priorityDate | 2008-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1551.