Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68ce827711a224df4f99d20865fc6f37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc90f838a9c3e112b957b1c0bc06ce35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b0f9ba4aed009d437c4e7fc1d2a116e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate |
2010-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6473a3766cdf2ac5bd5419fa6ce20bd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4785d450c42560f6c39d207d0e4e2cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88257cce5016e75ed452e19f12ce74be |
publicationDate |
2011-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011059478-A1 |
titleOfInvention |
Orphan Nuclear Receptor |
abstract |
The present invention relates to a novel human orphan nuclear receptor that binds to a cytochrome P-450 monooxygenase (CYP) promoter and that is activated by compounds that induce CYP gene expression. The invention further relates to nucleic acid sequences encoding such a receptor, to methods of making the receptor and to methods of using the receptor and nucleic acid sequences encoding same. The invention also relates to non-human animals transformed to express the human receptor and to methods of using such animals to screen compounds for drug interactions and toxicities. |
priorityDate |
1998-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |