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filingDate 2010-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a56dadf7b7b3cd59493ef9f08af7f60
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publicationDate 2011-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2011059114-A1
titleOfInvention Compositions and Methods for the Treatment of Radioresistant Glioma Stem Cells
abstract Compositions and uses of gamma secretase inhibitors (GSIs) for the treatment and inhibition of gliomas in subjects in need thereof are provided. Methods for administering gamma secretase inhibitors in association with radiation for the treatment of radiation resistant gliomas are described. Compositions for the inhibition of Notch signaling and activity are provided.
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